/structure and functions revised (e.g., the past, the presence and future of enzymology, biocatalysis, synthetic and systems biology),
/insights into enzyme mechanisms (e.g., promiscuous enzymes, tunnelling, reactions under extreme conditions, non-obvious modifiers),
/directed evolution and cascades (e.g., engineered enzymes, disordered proteins, moonlighting roles),
/upstream and downstream of reaction cascades (e.g., regulation of pathways and multi-enzyme cascades),
/prediction of structures and functions (e.g., data driven modelling and mining, incl. AI, structure prediction based on genomics and meta-genomics),
/high-performance systems and interesting applications.