Preparation of active pharmaceutical ingredients by mechanochemistry

Evelina Colacino / University of Montpellier

January 20, 2021, 2 - 3 pm CET

Evelina Colacino

Evelina Colacino is Associate Professor of Organic and Green Chemistry since 2013, at the University of Montpellier, France. Her main research activities concern the development of eco-friendly methodologies for the preparation of biomolecules, heterocyclic compounds and hybrid materials by mechanochemistry (dry or wet grinding), with a main focus on hydantoin scaffold and active pharmaceutical ingredients (medicinal mechanochemistry). She also investigates sustainable approaches to homogeneous or heterogeneous metal-catalysed processes by combining enabling technologies (ultrasounds, microwaves, and flow systems) with non-conventional media [e.g., glycerol, water, poly(ethylene)glycols, and PEG-based ionic liquids] or in micellar conditions (in water and glycerol).

She is also a promoter of sustainability in higher education by integrating green chemistry at undergraduate level in organic chemistry courses, with a special focus on the fundamentals and the practice of mechanochemistry.

Since 2019, she leads the European Programme COST Action CA18112 (Mech@SustInd) – "Mechanochemistry for Sustainable Industry" ( and