Bond Activations

Lutz Ackermann / Georg-August-University of Göttingen

July 7, 2021, 2 - 3 pm CEST


Oxidative C–H activation has emerged as an increasingly powerful tool in molecular syntheses. [1] Despite major progress towards atom and step economy, these transformations largely rely on precious metal catalysts and stoichiometric amounts of toxic metal oxidants, compromising the overall sustainability of the C–H activation strategy. In contrast, employing electrooxidation in lieu of reactive chemical oxidants prevents undesired waste formation through oxidant economy and offers efficient use of renewable energies from sustainable sources for chemical bond formation. [2] Inexpensive earth-abundant 3d metal [3] cobaltaelectrocatalysis set the stage for molecular syntheses at a unique level of resource economy. [4] Our studies towards metallaelectrocatalytic C–H and C–C activation will be discussed, with a topical focus on sustainable base metals. [5]


[1] a) L. Ackermann, Acc. Chem. Res. 2014, 47, 281–295; b) C. S. Yeung, V. M. Dong, Chem. Rev. 2011, 111, 1215–1292.
[2] a) P. Gandeepan, L. H. Finger, T. H. Meyer, L. Ackermann, Chem. Soc. Rev. 2020, 49, 4254–4272; b) L. Ackermann, Acc. Chem. Res. 2020, 53, 84-104., C. Ma, P Fang, T.-S. Mei, ACS Catal. 2018, 7179–7189; c) C. Zhu, N. W. J. Ang, T. H. Meyer, Y. Qiu, L. Ackermann, ACS Cent. Sci. 2021, 7, 415–431.
[3] P. Gandeepan, T. Müller, D. Zell, G. Cera, S. Warratz, L. Ackermann, Chem. Rev. 2019, 111, 2192–2452.
[4] a) Y. Qiu, M. Stangier, T. H. Meyer, J. C. A. Oliveira, L. Ackermann, Angew. Chem. Int. Ed. 2018, 57, 14179–14183; b) Y. Qiu, W.-J. Kong, J. Struwe, N. Sauermann, T. Rogge, A. Scheremetjew, L. Ackermann, Angew. Chem. Int. Ed. 2018, 57, 5828–5832.
[5] a) R. Mei, N. Sauermann, J. C. A. Oliveira, L. Ackermann, J. Am. Chem. Soc. 2018, 140; b) 7913–7921; N. Sauermann, T. H. Meyer, C. Tian, L. Ackermann, J. Am. Chem. Soc. 2017, 139, 18452–18455.

Lutz Ackermann

Lutz Ackermann studied Chemistry at Kiel University (Germany) and performed his PhD with Prof. Alois Fürstner at the Max-Planck-Institut für Kohlenforschung (Mülheim/Ruhr, Germany, 2001). After a postdoctoral stay at UC Berkeley with Prof. Robert G. Bergman, he initiated his independent research career in 2003 at the Ludwig-Maximilians-University München. In 2007, he became Full Professor (W3) at the Georg-August-University Göttingen. His recent awards and distinctions include the AstraZeneca Excellence in Chemistry Award (2011), an ERC Consolidator Grant (2012), the Gottfried Wilhelm Leibniz Prize (2017) and an ERC Advanced Grant (2021).

The development and application of novel concepts for sustainable catalysis constitutes his major current research interests, with a topical focus on electrocatalysis and bond activation.

He is an Associate Editor of the Beilstein Journal of Organic Chemistry since 2018.