STRENDA stands for “Standards for Reporting Enzymology Data”. For researchers it is essential to be able to compare, evaluate, interpret and reproduce experimental research results published in the literature and databases. Thus, for enzyme research, the STRENDA Commission has established standards for data reporting with the aim to improve the quality of data published in the scientific literature.
The STRENDA Guidelines were developed through extensive interactions with the biochemistry community to define the minimum information that is needed to correctly describe assay conditions (List Level 1A) and enzyme activity data (List Level 1B).
However, STRENDA aims neither to dictate or limit the experimental techniques used in enzymology experiments nor to establish a metric for judging the quality of experimental data, but to ensure that data sets are complete and validated, allowing scientists to review, reuse and verify them. The emphasis is on providing useful and reliable information.
With the aim to support authors to comprehensively report kinetic and equilibrium data from their investigations of enzyme activities, currently more than 50 international biochemistry journals already included the STRENDA Guidelines in their Instructions for Authors.
STRENDA supports authors by providing STRENDA DB – a web-based database whose data submission form automatically checks the manuscript data prior or during the publication process on compliance with the STRENDA Guidelines. The successful formal assessment is documented in a fact sheet that can be submitted with the manuscript to the journal. In addition, each dataset is assigned a DOI that allows referring and tracking the use of data. The data become publicly available in the database only after the corresponding article has been peer-reviewed and published in a journal.
The STRENDA Commission is continuously consulting the wider science community, reports the progress of its work and discusses new approaches regularly at the Beilstein Enzymology Symposia and in scientific journals.