This symposium broght together glycochemists and biologists with experts in bioinformatics and computer sciences not only to look back at the roots of glycosciences
30 odd years ago but also to gather the perspectives of present and future applications of glycomics.

Glycomics, in the past considered a subfield of proteomics, has established itself and evolved to become an independent discipline which studies systematically the structures and functions of glycans in a cell or organism.

Consequently, boundaries to proteomics, genomics and metabolomics are crossed towards a systems-wide investigation of the various roles of glycoconjugates in cell-cell communication, recognition processes, signal transduction, molecular trafficking, modulation and regulation of molecular pathways in both eukaryotes and prokaryotes and in many other processes such as diagnosis and therapy of diseases. Glycomics also encompasses further important areas, for example, combining bioinformatics and mathematics approaches to develop methods for data storage, analysis, and modelling functions and relationships.

Under the guidance of the MIRAGE Commission, this conference series also provides a platform to discuss current standards and needs for additional standards in the glycoscience. The mission of MIRAGE (www.beilstein-mirage.org) is to establish guidelines for the reliable and accurate reporting of glycan data and to interconnect existing and future infrastructure entities to provide the glycoscience community services for the deposition, sharing, analysis and reuse of glycan data.

The following aspects have been covered

/glycoproteomics

/glycan-linked diagnosis and therapy (markers and vaccines)

/methods for analysis and identification of glycoconjugates

/structure-function relationships of glycosylation patterns

/the metabolic art of directed glycosylation

/software tools for analysis and identification

/integration of data from glycomics, proteomics and genomics resources

No. 1

Exploring Protein N-glycosylation Alterations between Wild-type and Mutant Forms of Irisin
Joseph Zaia, Boston University

No. 2

Towards the Development of a Spatio-temporal O-Glycosylation Reporter Systems
Abdul H. Zafar, Imperial College London

No. 3

Modelling the Processing of Glycans on Secreted Glycoproteins
Daniel Ungar, University of York

No. 4

Mapping Glycosyltransferases Glycosylation Sites and Substrate Preferences via Glycoproteomics
Lucia Di Vagno, Imperial College London

No. 5

Evolution of the Interactions between Rotavirus VP8* and HBGAs: Insights from Computational Studies
Jesús Rodriguez-Diaz, University of Valencia

No. 6

Fine-tuning the Spike: Role of the Glycan Shield in the Structure / Dynamics of SARS-CoV-2S
Carl Fogarty, Maynooth University

No. 7

Simple, yet Logical Terms of N-glycans Meet the Emergence of Isomer-sensible Analysis
Friedrich Altmann, University of Natural Resources and Life Sciences, VIenna

No. 8

Towards Clinical O-glycomics: Application for Osteoarthrithis
Niclas Karlsson, Oslo Metropolitan University

No. 9

Exploring the Glycoproteome of the Sheep Myiasis Fly, Lucilia cuprina, for Novel Vaccine Targets
Edward Kerr, CSIRO, Brisbane

No. 10

Elucidating the O-glycan Structure of Tannerella serpentiformis
Stephanie Walcher, University of Natural Resources and Life Sciences, Vienna

No. 11

Wholistic Heparan Sulphate Oligosaccharide Profiling Using Top-down GAGomics
Marissa L. Maciej-Hulme, University of California San Diego

No. 12

Development of a Machine Learning Framework to Extract the Biomarker Potential of IgG N-glycans
Konstantinos Flevaris, Imperial College London

No. 13

Serum N-glycan Biomarkers Predict Patient Response to Vedolizumab Treatment for Crohn’s Disease
Georgia Elgood Hunt, Ludger Ltd., Oxford

No. 14

Integrated Glycomics and Genomics Reveals a Role for Plasma Protein and IgG N-glycosylation in Type 1 Diabetes Development
Najda Rudman, University of Zagreb

No. 15

Linking Glycosylation to Function
Catherine Hayes, Swiss Institute of Bioinformatics, Geneva

No. 16

Bioinformatics Analyses of Nematode Hexosaminidases
Zuzanna Dutkiewicz, University of Natural Resources and Life Sciences, Vienna

No. 17

A Bacterial Mannose Binding Lectin as a Tool for the Enrichment of C-and O-Mannosylated Peptides
Hans Bakker, Hannover Medical School

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No. 1

Privateer - Validation of Modelled Glycosylaton in the 3D Structural Biology Frontier
Haroldas Bagdonas, University of York

No. 2

Automated Glycopeptide Data Processing and Curation in Ghih Sensitivity Applications
David Falck, Leiden University Medical Center

No. 3

A Demonstration of CarbArrayART, a Tool for Glycan Microarray Data Management and Reporting
Yukie Akune, Imperial College London

No. 4

What's new on Glyco@Expasy?
Frédérique Lisacek, Swiss Institute of Bioinformatics, Geneva

No. 5

GlycoDomainViewer, Glycopacity and Glyco.me
Hiren J. Joshi, University of Copenhagen

No. 6

GlyFinder: An Online Tool for Finding Glycans and Glycoproteins in the PDB
Robert Woods, University of Athens, USA

No. 7

GlyGen Portal, Glycan Array Data Repository and the Glycoinformatics Consortium
René Ranzinger, University of Athens, USA

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