- unravelling the complexity of structures and functions of glycoconjugates,
- development of glycan-based vaccines
- glycans as markers to detect viruses, pathogens etc.,
- diagnosis of glycan-related diseases,
Time-proof perspectives on Glycoscience
Beilstein Glyco-Bioinformatics Symposium 2019
25 – 27 June, 2019
Dom Hotel, Limburg, Germany
The Glyco-Bioinformatics Symposium 2019 brought together glycochemists and biologists with experts in bioinformatics and computer sciences.
Scientific Program:
Kiyoko Aoki-Kinoshita / Soka University Tokyo, Japan
Matthew Campbell / Griffith University, Gold Coast, Australia
Frédérique Lisacek / Swiss Institute for Bioinformatics, Geneva, Switzerland
Joseph Zaia / Boston University, USA
Carsten Kettner / Beilstein-Institut
Topics 2019
- integration of data from glycomics, proteomics and genomics resources,
- strategies for mining and analysing large data sets and high-throughput data,
- software tools for data storage, analysis, mining and sharing
Scientific Program
Structural Investigations of the Roles of Glycans in Infection, Immunity and Cancer
Catherine E. Costello, Boston University Medical School
Glycome of Stem Cells: From Structural Analysis to Social Implementation
Hiroaki Tateno, National Institute of Advanced Industrial Science and Technology (AIST)
Poster Lightning Talks #1
(Posters 1–4)
Mining Glycan Microarray Data using Anti-carbohydrate Binding of Antibodies in Human Serum
Richard D. Cummings, Harvard Medical School
Targeting Siglecs to Suppress Allergies
James C. Paulson, The Scripps Research Institute
Software Elevator Talks #1
(Software 1–3)
Giant dsDNA Viruses Taste for Sugars
Cristina de Castro, University of Napoli
Understanding the Molecular Details of Mucin-type O-Gycosylation by Glycosyltransferase Bump-and-hole Engineering
Benjamin Schumann, Imperial College London
Poster Lightning Talks #2
(Posters 5–8)
Glycoprotein Data Visualization in GlyCosmos
Kiyoko Aoki-Kinoshita, Soka University
Challenges for the CAZy Database in the Era of High-throughput Sequencing and Functional Screening
Nicolas Terrapon, Aix-Marseille University,
Some (in)consistency Issues in Grouping Glyco-entities
Frédérique Lisacek, SIB Swiss Institute of Bioinformatics
Software Elevator Talks #2
(Software 4–5)
Poster Lightning Talks #3
(Posters 9–12)
Standardization of Glycosaminoglycan (GAG) Sequences binding to Proteins and Creation of a Pipeline for the Curation of GAG-protein Interactions: Application to GAG Interaction Networks
Sylvie Ricard-Blum, University Lyon 1
Glycomics and Proteomics of Brain Pathologies
Joe Zaia, Boston University
Contextualized Functions of Glycans in Human Tissue Formation
Hans H. Wandall, University of Copenhagen
Challenges in Defining the Structure and Function of Invertebrate N-Glycans
Iain B.H. Wilson, Universität für Bodenkultur
Software Elevator Talks #3
(Software 7–8)
Software Demo Session
Sugars in the Gas Phase – from Structure to Reaction Mechanism
Kevin Pagel, Freie Universität Berlin
Glycomimetic Tools to Understand Decoding of the Glycan Code
Christopher Rademacher, MPI for Colloids and Interfaces
Dimensions of Glycomimetics
Thisbe K. Lindhorst, Christiana Albertina University Kiel
Glycans as Biomarkers and Functional Effectors in Diabetes and Cardiovascular Diseases
Gordan Lauc, University of Zagreb
Update on the 1st Human Glycoproteomics Initiative (HUPO/HGI) Study: Interlaboratory Evaluation of Software for Intact Glycopeptide Analysis by MS
Nicolle H. Packer,Macquarie University
Glycoscience in the Algae
Robert A. Field, John Innes Centre
Carbohydrates and Glycomimetics from the Viewpoint of a Computational Chemist
Martin Frank, Biognos AB
From Symbolic Carbohydrate Notations to Atomic Coordinates
Philip Toukach, Zelinsky Institute of Organic Chemistry
GlyGen - Computational and Informatics Resources for Glycosciences
René Ranzinger, University of Athens
Introducing UniCarbKB 2.0 and SPRIT-Gly
Matthew Campbell, Griffith University
GlyFinder and GlyProbity: New Online Tools for Locating and Curating Carbohydrate Structures in wwPDB
Rob Woods, University of Athens
O-Glycologue: a Simulator of the Enzymes of O-linked Glycosylation
Andrew McDonald, Trinity College Dublin
MIRAGE Presentation and Workshop Discussion
René Ranzinger and Carsten Kettner
Poster Presentations
UniLectin3D, a Database of Carbohydrate Binding Proteins with Curated Information on 3D Structures and Interacting Ligands
François Bonnardel
The Raspberry Synthesizer: An Open Source Chemical Laboratory Toolbox where IoT 4.0 meets Chemistry
Frank Schuhmacher
Targeting CD22 with Sialic Acid Derivatives
June Ereño Orbea
Predicting N-Glycan Processing based on Enzyme-glycan Accessibility
Oliver Grant
Modelling Glycan Processing to Probe Golgi-enzyme Organization
Daniel Ungar
Isobaric and Isomeric Glycans – m/z alone is not enough
Katharina Paschinger
RAMZIS: Ranking Assessment of m/z Identifications by Similiarity
William E. Hackett
DIALib, an Automated Workflow for Theoretical Ion Library Generation for Peptides and Glycopeptides
Toan Phung
Altered O-linked Glycosylation in Osteoarthrithis Influence Galectin-3 Organization of the Lubrication of the Cartilage
Niclas G. Karlsson
GlyConvert – Bridging Glycoinformatics and Cheminformatics
Pavla Suchánkova
In-silico Understanding of Glycosylation through Automation and Machine Learning
Sooyeon Moon
GlyConnect Compozitor – an Interactive Graph of Glycan Compositions
Julien Mariethoz
Software Demonstrations
Two Software Solutions for Automated Structural Characterization of Glycans Using either HILIC-UPLC-MS or HILIC-UPLC-IMS-MS Glycomics Workflows
Ian Walsh
Anyone Can Display Glycan Symbols in 3D Structures: 3D-SNFG in LiteMol
Oliver Grant
An Update on new Glycan Array Data Software CarbArrayART: ready for Beta Testingnd Play’ with Machine Learning
Yukie Akune
The MIRAGE Compatible UniCarb-DR Repository for MS Glycomics
Niklas G. Karlsson
Bioinformatics Tools for Glycoscience
René Ranzinger
‘Plug and Play’ with Machine Learning
Sourav Chatterjee
GlyConnect, the Power Engine of Glycomics@ExPASy
Julien Mariethoz
GlyCosmos Portal and GLIC
Kiyoko Aoki-Kinoshita
Impressions
Photos taken by Pavla Suchánková