Time-proof perspectives on Glycoscience

Beilstein Glyco-Bioinformatics Symposium 2019

25 – 27 June, 2019

Dom Hotel, Limburg, Germany

The Glyco-Bioinformatics Symposium 2019 brought together glycochemists and biologists with experts in bioinformatics and computer sciences.

Scientific Program:

Kiyoko Aoki-Kinoshita / Soka University Tokyo, Japan

Matthew Campbell / Griffith University, Gold Coast, Australia

Frédérique Lisacek / Swiss Institute for Bioinformatics, Geneva, Switzerland

Joseph Zaia / Boston University, USA

Carsten Kettner / Beilstein-Institut

 

 

Topics 2019

  • unravelling the complexity of structures and functions of glycoconjugates,

  • development of glycan-based vaccines

  • glycans as markers to detect viruses, pathogens etc.,

  • diagnosis of glycan-related diseases,

  • integration of data from glycomics, proteomics and genomics resources,

  • strategies for mining and analysing large data sets and high-throughput data,

  • software tools for data storage, analysis, mining and sharing

Scientific Program

Structural Investigations of the Roles of Glycans in Infection, Immunity and Cancer
Catherine E. Costello, Boston University Medical School

Glycome of Stem Cells: From Structural Analysis to Social Implementation
Hiroaki Tateno, National Institute of Advanced Industrial Science and Technology (AIST)

Poster Lightning Talks #1
(Posters 1–4)

Mining Glycan Microarray Data using Anti-carbohydrate Binding of Antibodies in Human Serum
Richard D. Cummings, Harvard Medical School

Targeting Siglecs to Suppress Allergies
James C. Paulson, The Scripps Research Institute

Software Elevator Talks #1
(Software 1–3)

Giant dsDNA Viruses Taste for Sugars
Cristina de Castro, University of Napoli

Understanding the Molecular Details of Mucin-type O-Gycosylation by Glycosyltransferase Bump-and-hole Engineering
Benjamin Schumann, Imperial College London

Poster Lightning Talks #2
(Posters 5–8)

Glycoprotein Data Visualization in GlyCosmos
Kiyoko Aoki-Kinoshita, Soka University

Challenges for the CAZy Database in the Era of High-throughput Sequencing and Functional Screening
Nicolas Terrapon, Aix-Marseille University,

Some (in)consistency Issues in Grouping Glyco-entities
Frédérique Lisacek, SIB Swiss Institute of Bioinformatics

Software Elevator Talks #2
(Software 4–5)

Poster Lightning Talks #3
(Posters 9–12)

 

 

Standardization of Glycosaminoglycan (GAG) Sequences binding to Proteins and Creation of a Pipeline for the Curation of GAG-protein Interactions: Application to GAG Interaction Networks
Sylvie Ricard-Blum, University Lyon 1

Glycomics and Proteomics of Brain Pathologies
Joe Zaia, Boston University

Contextualized Functions of Glycans in Human Tissue Formation
Hans H. Wandall, University of Copenhagen

Challenges in Defining the Structure and Function of Invertebrate N-Glycans
Iain B.H. Wilson, Universität für Bodenkultur

Software Elevator Talks #3
(Software 7–8)

Software Demo Session

Sugars in the Gas Phase – from Structure to Reaction Mechanism
Kevin Pagel, Freie Universität Berlin

Glycomimetic Tools to Understand Decoding of the Glycan Code
Christopher Rademacher, MPI for Colloids and Interfaces

Dimensions of Glycomimetics
Thisbe K. Lindhorst, Christiana Albertina University Kiel

 

Glycans as Biomarkers and Functional Effectors in Diabetes and Cardiovascular Diseases
Gordan Lauc, University of Zagreb

Update on the 1st Human Glycoproteomics Initiative (HUPO/HGI) Study: Interlaboratory Evaluation of Software for Intact Glycopeptide Analysis by MS
Nicolle H. Packer,Macquarie University

Glycoscience in the Algae
Robert A. Field, John Innes Centre

Carbohydrates and Glycomimetics from the Viewpoint of a Computational Chemist
Martin Frank, Biognos AB

From Symbolic Carbohydrate Notations to Atomic Coordinates
Philip Toukach, Zelinsky Institute of Organic Chemistry

GlyGen - Computational and Informatics Resources for Glycosciences
René Ranzinger, University of Athens

Introducing UniCarbKB 2.0 and SPRIT-Gly
Matthew Campbell, Griffith University

GlyFinder and GlyProbity: New Online Tools for Locating and Curating Carbohydrate Structures in wwPDB
Rob Woods, University of Athens

O-Glycologue: a Simulator of the Enzymes of O-linked Glycosylation
Andrew McDonald, Trinity College Dublin

MIRAGE Presentation and Workshop Discussion
René Ranzinger and Carsten Kettner

Poster Presentations

UniLectin3D, a Database of Carbohydrate Binding Proteins with Curated Information on 3D Structures and Interacting Ligands
François Bonnardel

The Raspberry Synthesizer: An Open Source Chemical Laboratory Toolbox where IoT 4.0 meets Chemistry
Frank Schuhmacher

Targeting CD22 with Sialic Acid Derivatives
June Ereño Orbea

Predicting N-Glycan Processing based on Enzyme-glycan Accessibility
Oliver Grant

Modelling Glycan Processing to Probe Golgi-enzyme Organization
Daniel Ungar

Isobaric and Isomeric Glycans – m/z alone is not enough
Katharina Paschinger

RAMZIS: Ranking Assessment of m/z Identifications by Similiarity
William E. Hackett

DIALib, an Automated Workflow for Theoretical Ion Library Generation for Peptides and Glycopeptides
Toan Phung

Altered O-linked Glycosylation in Osteoarthrithis Influence Galectin-3 Organization of the Lubrication of the Cartilage
Niclas G. Karlsson

GlyConvert – Bridging Glycoinformatics and Cheminformatics
Pavla Suchánkova

In-silico Understanding of Glycosylation through Automation and Machine Learning
Sooyeon Moon

GlyConnect Compozitor – an Interactive Graph of Glycan Compositions
Julien Mariethoz

Software Demonstrations

Two Software Solutions for Automated Structural Characterization of Glycans Using either HILIC-UPLC-MS or HILIC-UPLC-IMS-MS Glycomics Workflows
Ian Walsh

Anyone Can Display Glycan Symbols in 3D Structures: 3D-SNFG in LiteMol
Oliver Grant

 

An Update on new Glycan Array Data Software CarbArrayART: ready for Beta Testingnd Play’ with Machine Learning
Yukie Akune

The MIRAGE Compatible UniCarb-DR Repository for MS Glycomics
Niklas G. Karlsson

Bioinformatics Tools for Glycoscience
René Ranzinger

‘Plug and Play’ with Machine Learning
Sourav Chatterjee

GlyConnect, the Power Engine of Glycomics@ExPASy
Julien Mariethoz

GlyCosmos Portal and GLIC
Kiyoko Aoki-Kinoshita

Impressions

Photos taken by Pavla Suchánková