If you come from the east, e.g. Gießen, Kassel, Hannover, or Berlin, leave the A5 at the motorway junction 8 'Reiskirchener Dreieck', change to A480 and follow the signs to Limburg. You will be guided via B429 to B49 (later becomes B54) which brings you directly to Limburg.
In order to avoid navigating through the city and get lost in the many one-way streets, it is recommended to change to the motorway A3 into the direction Frankfurt before entering the city. Leave the A3 at the exit "Limburg Süd" and follow the instructions above.
By train
Limburg has two train stations; "Limburg (Lahn)" for regional trains and "Limburg-Süd" for high-speed trains.
High-speed trains connect the airports Cologne and Frankfurt with Limburg.
If appropriate it is recommended to take the high-speed trains. From Frankfurt the train takes about 20 min. You start from "Frankfurt am Main Flughafen Fernbahnhof" (for long distance trains), leave the train at "Limburg-Süd" and take a taxi to the Dom Hotel. From the airport "Köln/Bonn Flughafen", the train takes about 1 hr. Leave the train at "Limburg-Süd" and take a taxi to the Dom Hotel.
Alternatively, you can take the regional train to Limburg. Take a regional train at the Frankfurt airport "Frankfurt(M) Flughafen Regionalbahnhof" to Frankfurt central station and change to the regional trains (RB22 or RE20) to "Limburg (Lahn)". This train takes about 1 hr from Frankfurt central station to Limburg. From "Limburg (Lahn)" station it is a 10 min walk to the Dom Hotel.
Exit the station, cross the bus terminal and enter into "Bahnhofstraße". Follow this street (which crosses a market place) and cross Grabenstraße. Then the hotel will be on the right hand side.