Chemical Structures 

The Beilstein Journals are one of the first chemistry journals to extract and disseminate machine-readable chemical structures and the first to include these structures as FAIR chemical data in published articles. As of February 2025 we make chemical semantics machine-readable and accessible to bots and crawlers, meaning that chemical structure information can be automatically processed from articles within the limits of current chemical standards. Within our publishing workflow, chemical structures extracted from ChemDraw files provided by authors and are curated and digitized, then embedded as metadata in the full text HTML and XML versions of the published articles.

The structures become Findable - thanks to the InChI standard. They are Accessible by identifier and standard protocols. This work is Interoperable as we have used JSON-LD and vocabularies/schemas from Schema.org. And importantly, structures are Reusable as all information in the Beilstein Journals has been published under a CC BY Attributions License.

Of note is that the InChI standard is critical for this work – the incorporation of InChI strings makes the structures more easily findable and interoperable and provides a link between human- and machine-readable chemical information. In addition, the extracted chemical structures of published articles are delivered to PubChem, supporting the world's largest freely accessible chemical database.

In future releases, we plan to extend the extraction work to reactions and Markush structures and provide chemical data for already published articles from past volumes. Furthermore, after consultation with the chemistry community, we intend to display the structures and related information directly on our journal webpages. We have also ensured that all tools and software related to this project that were developed in-house are available for free to the chemistry community with an open source license.