On December 5, 2022, a fire destroyed the historic experiment table in the lecture hall of Justus Liebig's originally preserved laboratory. The analytical and pharmaceutical laboratory as well as the library were also affected by the fire.
After determining the cause of the fire, intent and negligence could be ruled out and the volunteers were able to start with the cleaning and reconstruction work. The first stage – the cleaning of the ceilings and walls – was completed at the end of January 2023. This was followed by the cleaning of sensitive exhibits and the authentic new construction of Liebig's experiment table. The safety and electrical systems will also be replaced as part of the reconstruction work. After the renovation, the museum will reopen regularly.