The Chemical Theatre of Biological Systems
May 24th - 28th, 2004, Bozen, Italy
Program
Martin G. Hicks: Opening Remarks and Greetings
Session Chair: Trevor Howe
Steven V. Ley: Evolution or Revolution: The Challenge to Today's Medicinal Chemist
Keith Russel:The Value of Chemical Genetics in Drug Discovery
Hugo Kubinyi:Changing Paradigms in Drug Discovery
Ernesto Freire:Thermodynamic-based Algorithms in Drug Design. High Affinity, Selectivity and Adaptability
Session Chair: Carsten Kettner
Jason Micklefield:Combinatorial Biosynthesis of Nonribosomal Lipopeptides
Virginia Cornish: Chemical Complementation: A Genetic Assay for Protein Evolution and Proteomics
Peter Willett: Using Structural Similarity in the Search for Bioactivity
Konrad H. Bleicher: Small-Molecule Lead Generation in the 21st Century
Session Chair: Timothy Clark
Nicholas J. Westwood: Chemical Approaches in Cellular Microbiology
Johann Gasteiger: Multidimensional Exploration into Biochemical Pathways
Chandra Verma: In-silico Protein-Ligand Dynamics: New Paradigms
Thomas D. Schneider: Molecular Information Theory: From Clinical Applications to Molecular Machine Effect
Session Chair: John Bradshaw
Athel Cornish-Bowden: Handling Far-From-Equilibrium Processes in Metabolic Models
Alan E. Mark: Simulating Self-Organization in Biomolecular Systems
Thomas S. Leyh: Catalytic Strategies for the Activation of Sulfate
Gisbert Schneider: Navigation in Chemical Space
Session Chair: Karl-Heinz Baringhaus
Richard A. Goldstein: Evolutionary Perspectives on Protein Folding, Structure and Dynamics
Alex J. MacDonald: Modelling and Simulation of Pharmocokinetic and Pharmacodynamic Systems - Approaches in Drug Discovery
Kevin Davies: Summary and Closing Remark
