Scientific Program

Talks

There will be a welcome reception on Tuesday, 4 October at 6 pm followed by a dinner at 7 pm.

 

WEDNESday, 5 OCTOber

 

9:00
Welcome and Introduction 

NEW NUCLEIC ACID BUILDING BLOCKS
Session chair: Nathan Luedtke

9:20
Modified nucleic acids for crosslinking and catalysis
Annemieke Madder / Ghent University, Belgium

10:00
Sequence-specific labeling of DNA with methyltransferases and cofactor analogues
Elmar Weinhold / RWTH Aachen University, Germany

10:40
Coffee break

11:00
Trinucleotide phosphoramidites: Superior building blocks for the synthesis of controlled randomized gene libraries
Sabine Müller / University of Greifswald, Germany

11:40
Polymerase synthesis of base-modified nucleic acids: New methods and new applications
Michal Hocek / Academy of Sciences, Prague, Czech Republic

12:20
Lunch

 

NUCLEIC ACID ANALOGS AND LIPIDS
Session chair: Oliver Seitz

14:00
Nucleolipids: Synthesis, biomedical activity, and hydrophobization tools for nucleic acids for their incorporation into artificial lipid membranes
Helmut Rosemeyer / University of Osnabrück, Germany

14:40
Pyrrolidinyl peptide nucleic acids with a/β-peptide backbone: Synthesis, properties and applications
Tirayut Vilaivan / Chulalongkorn University, Bangkok, Thailand

15:20
Coffee break

15:40
D-L-aTNA and SNA as a new class of acyclic XNA
Hiroyuki Asanuma / Nagoya University, Japan

16:20
Playing chemistry on nucleic acids and their peptide conjugates
Jesper Wengel / University of Southern Denmark, Odense, Denmark

17:00
End

18:00
Dinner

 

POSTER SESSION

20:00
Presentation and discussion of all posters

22:00
End

 

 

Thursday, 6 october

 

LIGHT-DRIVEN AND FLUORESCENT FUNCTIONALITIES
Session chair: Hiroyuki Asanuma

9:00
Bioorthogonal chemical reporters of DNA metabolism
Nathan Luedtke / University of Zurich, Switzerland

9:40
Enhanced hybridization probes for RNA imaging
Oliver Seitz / Humboldt University Berlin, Germany

10:20
Coffee break

10:40
Reversible in situ generation of DNA-binding cationic hetarenes
Heiko Ihmels / University of Siegen, Germany

11:20
DNA-inspired supramolecular materials
Robert Häner / University of Bern, Switzerland

12:00
Light-driven functions in DNA
Hans-Achim Wagenknecht / Karlsruhe Institute of Technology, Germany

12:40
Lunch

 

14:00
EXCURSION

19:00
Dinner

 

FRIday, 7 OCTOber

 

NEW NUCLEIC ACID ARCHITECTURES AND BASE PAIRS
Session chair: Hans-Achim Wagenknecht

9:00
Metal-mediated base pairing using 1H-imidazo[4,5-f][1,10]phenanthroline as artificial nucleobase
Jens Müller / University of Münster, Germany

9:40
Peptido RNA from ribonucleotides and amino acids
Clemens Richert / University of Stuttgart, Germany

10:20
Coffee break

10:40
Chemical ligation of DNA, biocompatibility and applications of artificial backbones
Tom Brown / University of Oxford, UK

11:20
Unusual DNA bases in our genomes
Thomas Carell / LMU Munich, Germany

12:00
Lunch

 

 

 

RNA AND CATALYTICALLY ACTIVE NUCLEIC ACIDS
Session chair: Jesper Wengel

13:30
A chemical biology perspective on the 5' cap
Andrea Rentmeister / University of Münster, Germany

14:10
Strategies for site-directed spin labeling of nucleic acids
Snorri Sigurdsson / University of Iceland, Reykjavik, Iceland

14:50
Coffee break

15:10
The structural basis of DNA catalysis
Claudia Höbartner / University of Göttingen, Germany

15:50
Modifying RNA to explore riboswitch and ribozyme function
Ronald Micura / University of Innsbruck, Austria

16:30
End

19:00
Dinner

Poster

No. 1:
Manipulation of the mRNA 5’-cap at the N7 position as valuable platform for RNA labeling, translation and interaction studies
Lea Anhäuser / University of Münster

No. 2:
Distance dependency of thymine-thymine-dimer formation in benzophenone-modified DNA
Linda Antusch / Karlsruhe Institute of Technology

No. 3:
Alkene-tetrazine ligation as a tool for DNA labeling
Anna Bujalska / University of Zurich

No. 4:
Interstrand crosslinking of DNA using strain-promoted click chemistry
Zahra Harati Taji / University of Zurich

No. 5:
Developing emissive isomorphic nucleosides
Aaron Johnson / University of Zurich

No. 6:
Synthesis and structural elucidation of Formycin A-nucleolipids
Christine Knies / University of Osnabrück

No. 7:
Click-linked DNA for one-pot gene synthesis
Mikiembo Kukwikila / University of Southampton

No. 8:
Triazole-linked locked nucleic acids
Pawan Kumar / University of Oxford

No. 9:
Synthesis and genetic selection of acyclic oxomethylenephosphono oligonucleotides (ONA)
Min Luo / KU Leuven

No. 10:
Synthesis of chemical tools for targeted epigenetic modifications
Ha Phuong Nguyen / University College London

No. 11:
Double-headed nucleotides as new building blocks for nucleic acid architectures
Poul Nielsen / University of Southern Denmark

No. 12:
New strategies for the label-free optical detection of oliginucleotides or antibodies with surface plasmon fluorescence spectroscopy
Gilbert Nöll / University of Siegen

No. 13:
Electrochemically switchable protein-DNA layers
Gilbert Nöll / University of Siegen

No. 14:
Aggregation-inclined dyes as resource of multitarget-probes for DNA and RNA
Ivo Piantanida / Ruđer Bošković Institute

No. 15:
Structural basis of the mispairing of an artificially expanded genetic information system
Linus Reichenbach / University of Strathclyde

No. 16:
Kinetic and thermodynamic stabilities of T-HgII-T base pairs: Inhibition of DNA polymerases
Olivia Schmidt / University of Zurich

No. 17:
New insights into 8-Vinyl-2‘-Deoxyguanosine and 8-Vinyl-Guanosine
Julia Schneider / University of Göttingen

No. 18:
Synthesis and optical properties of cyanine dyes as wavelength-shifting fluorescent DNA and siRNA probes
Jeannine Steinmeyer / Karlsruhe Institute of Technology

No. 19:
Berberine dimer as a turn-on fluorescent G-quadruplex ligand by its conformational change
Masayuki Tera / Suntory Foundation for Life Sciences

No. 20:
Temperature-controlled and programmable fusion of liposomes
Stefan Vogel / University of Southern Denmark

No. 21:
Development of bright fluorescent base analogues for applications in FRET
Marcus Wilhelmsson / Chalmers University of Technology