Translational Trends in Nanomedicine

Beilstein Nanotechnology Symposium 2018

17 – 19 September, 2018
Hotel Jagdschloss Niederwald, Ruedesheim, Germany

 

Scientific Program:

Joerg Lahann / University of Michigan

Luis Liz-Marzán / CIC biomaGUNE, San Sebastian

Francesco Stellacci / EPFL, Lausanne

Molly Stevens / Imperial College London

 

Summary

The Beilstein Nanotechnology Symposium “Translational Trends in Nanomedicine” took place at a beautiful “hunters castle” surrounded by forests with an ecstatic view of the Rhein valley. The highlight of the conference was its small size, enabling fruitful scientific discussions and one-to-one interactions in a stimulating environment. The speakers collectively provided an excellent overview on the use of nanomaterials for advancements in the field of drug delivery, bio-imaging, anti-viral therapeutics, and regenerative medicine. The talks were broadly categorized into three topics: (i) the use of nanoparticles for targeted delivery and imaging, (ii) hybrid materials for nanomedicine and regenerative medicine, and (iii) peptide assemblies and their mimicries as biomaterials. The conference was structured such that the use of nanomaterials for in vivo applications to their supramolecular assemblies as materials was chronologically covered. Certain challenging uses of nanomaterials, for example, the use of nanoparticles for brain targeting, their interaction with cells, using nanoneedles to understand cell–surface interactions, and nanostraws for direct cell delivery were highlighted. Furthermore, a few talks focused on the use of novel nanosystems for tackling viral infections/diseases, for which a cure remains inaccessible for the larger part. In addition, emphasis was laid on translational aspects of nanomedicine, i.e., transferring research from laboratory to the clinics, giving a realistic perspective to the ongoing research in the field of nanomedicine.

From nanomaterials to peptide assemblies, important considerations with respect to their cellular interactions and in turn their toxic effects were presented. An insight into the biological activity relationship of rare earth oxides that are used for bioimaging was an interesting perspective for all researchers as it concerns most work done in the field of nanotoxicity.

Apart from the scientific talks, an excellent poster session covered a range of topics from the design of nanomaterials such as nanoneedles and nanoparticles, to their applications in cell transfection and for nanomedicine, respectively. This interactive session was the perfect platform for young researchers to engage with their peers and professors for initiating collaborations and developing further ideas for their research. Taking full advantage of the beautiful venue, we enjoyed a pleasant hiking trip through the vineyards tasting authentic wine from the region.

In a nutshell, the symposium on “Translational Trends in Nanomedicine” was a rewarding experience in terms of research excellence, scientific discussions, selected group of participants, outstanding location, and a wonderful and engaging atmosphere!

Nanomedizin Gruppe

Scientific Program

Talks

 

MONday, 17 SEPTEMBER

9:00
Welcome and Introduction

Session chair: Francesco Stellacci

9:20
Brain-targeting nanoparticles
Joerg Lahann / University of Michigan, USA

10:00
Nanoparticles for cell tracking applications: some basic considerations
Neus Feliu / University of Hamburg, Germany

10:40
Coffee break

11:10
Degradation of nanoparticles effects their colloidal properties and interaction with cells
Wolfgang Parak /University of Hamburg, Germany

11:50
Imaging with plasmonic nanoparticles
Luis Liz-Marzán /CIC biomaGUNE, Spain

12:30
Lunch

Session chair: Luis Liz-Marzán

13:50
Use of composite nanoparticles for the inhibition of viral infections
Ronit Sarid / Bar-Ilan University, Israel

14:30
Multivalent nanosystems as potent influenza virus inhibitors
Daniel Lauster / Free University of Berlin, Germany

15:10
Coffee break

15:40
Nanotechnology to develop novel antivirals
Francesco Stellacci / EPFL, Switzerland

16:20
POSTER INTRODUCTION
Short presentation of all posters

 

POSTER SESSION

18:00
Presentation and discussion of all posters

20:00
Dinner

 

TUESDAY, 18 SEPTEMBER

Session chair: Nicholas Melosh

9:00
Bio-responsive hybrid materials for regenerative medicine and biosensing
Molly M. Stevens / Imperial College London, UK

9:40
Nanomedicine based on DNA hybrid materials and supercharged polypeptides
Andreas Herrmann / DWI - Leibniz Institute for Interactive Materials, Germany

10:20
Coffee break

10:50
Crystallization pathways for protein crystals and colloidal assemblies
Sharon C. Glotzer / University of Michigan, USA

11:30
Targeting drug carriers in the vasculature
Vladimir Muzykantov / University of Pennsylvania, USA

12:10
Lunch

 

13:50
EXCURSION

17:30
End of excursion

19:00
Dinner

 

WEDNESday, 19 SEPTEMBER

Session chair: Molly M. Stevens

9:00
Emerging concepts in clinical nanomedicine: hemodynamics and modulation of innate immunity
Joy Wolfram / Mayo Clinic, USA

9:40
Supramolecular engineering strategies to bridge nanoscale design and macroscopic applications
Alvaro Mata / Queen Mary University of London, UK

10:20
Coffee break

10:50
Nanophotonic metasurfaces for next generation biosensors

Hatice Altug / EPFL, Switzerland

11:30
Nanostraw mediated non-perturbative cell access and transfection
Nicholas Melosh / Stanford University, USA

12:10
Lunch

Session chair: Joerg Lahann

13:30
Biomimetic nanostructures as functional biomaterials
Nicholas A. Kotov / University of Michigan, USA

14:10
Non-invasive elastic property measurement of soft matter
John Kieffer / University of Michigan, USA

14:50
Coffee break

15:20
Peptide-triggered gene transfer in musculoskeletal regeneration
Millicent O. Sullivan / University of Delaware, USA

16:00
Integrated nanosafety considerations in developing nanomedicine applications
Tian Xia / University of California, USA

16:40
Final words, farewell

16:50
End of program

19:00
Dinner

Poster

No. 1:
Exploring new nanoneedle techniques for enhanced cell transfection
Michele Becce / Imperial College London

No. 2:
Protein-mediated synthesis of anisotropic nanoparticles and their application as ROS scavengers
Mustafa ElGharib / University of Hamburg

No. 3:
The use of 3D cell models to investigate nanomedicine uptake and imaging thereof
Malou Henriksen-Lacey / CIC biomaGUNE

No. 4:
Virucidal nanomaterials targeting influenza virus
Özgün Kocabıyık / EPFL

No. 5:
Detection of metabolic interactions in the tumour environment by surface-enhanced resonance Raman scattering
Javier Plou / CIC biomaGUNE

No. 6:
Fabrication of functional nanostructured materials for patterned
bio-immobilization
Divya Varadharajan / Karlsruhe Institute of Technology

No. 7:
Towards controlled polymer brushes for nanomedicine
Gowthamy Venkidasubramonian / Karlsruhe Institute of Technology

No. 8:
Integrity of dye conjugated iron oxide nanoparticles in presence of different enzymes
Lin Zhu / University of Hamburg