Scientific Program


Tuesday, 19 Sept.


9.00
Opening

9.15
Structural Mechanism for the Fidelity Modulation of DNA Polymerases
Ming-Daw Tsai, Academia Sinica, Taipei, Taiwan

9.55
Insights from a Global Analysis of the Structure-function Relationships in the Tautomerase Superfamily
Christian P. Whitman, The University of Texas at Austin

10.35
Poster Flash Presentations
(Posters 1-4)

10.55
Coffee Break

11.15
Interleukin-6 and ADAM17 in the Control of Inflammation and Cancer
Stefan Rose-John, University of Kiel

11.55
Structural Basis for Regulation in the Aromatic Amino Acid Hydroxylases
Paul F. Fitzpatrick, University of Texas Health Science Center, San Antonio, TX

12.35
Lunch

13.50
Viral-encoded Receptor Proteins Rewire Cellular Signalling
Martine J. Smit, VU Universiteit Amsterdam

14.30
A Novel Role for Small Non-coding RNA in the DNA Damage Response: Characterization of DROSHA Recruitment to DNA Breaks
Sofia Francia, IFOM - The FIRC Institute of Molecular Oncology, Milano

15.10
Transcription Initiation Complex and Genetic Disorders
Jean-Marc Egly, University of Strasbourg

15.50
Tea Break

16.10
The Dynamic Epigenome: Mechanisms Governing Stepwise Oxidation of 5-mathylcytosine by TET Family Enzymes
Rahul Kohli, University of Pennsylvania, Philadelphia, PA

16.50
Enzyme Conformational Dynamics Control HIV Reverse Transcriptase Specificity and Evolution of Drug Resistance
Kenneth A. Johnson, The University of Texas at Austin

17.30
Poster Session

19.30
Dinner

 

 


Wednesday, 20 Sept.


9.00
How Integrated Annotation in Diverse Databases with Enzyme Information Can Provide Translational Science
Claire O'Donovan, EMBL-EBI, Cambridge

9.40
CETCH Me If You Can: Bringing Inorganic Carbon into Life with Synthetic CO2 Fixation
Tobias Erb, MPI for Terrestrial Microbiology, Marburg

10.20
Adaptation of Phosphatases as Regulators, Catalysts, and Housekeepers
Karen N. Allen, Boston University

11.00
Coffee Break

11.20
Evolutionary Diversification of Protein-protein Interactions by Interface Add-ons
Reinhard Sterner, University of Regensburg

12.00
Design and Evolution of New Biocatalysts for Enantionselective Synthesis
Nicholas Turner, The University of Manchester

12.40
Design and Evolution of Artificial Enzymes
Donald Hilvert, ETH Zurich

13.20
Lunch

14.30
Excursion

19.30
Dinner


Thursday, 21 Sept.


9.00
Nature's Strategies in the Regulation of Enzyme Activity by Modifiers Examined under the Magnifying Glass
Antonio Baici, University of Zurich

9.40
Multi-level Regulation of Metabolic Enzymes During Biological Ageing
Barbara M. Bakker, University Medical Center Groningen

10.20
Biosynthesis of the O-Methyl Phosphoramidate Modifications to the Capsular Polysaccharides of Campylobacter jejuni
Frank M. Raushel, Texas A&M University, College Station, TX

11.00
Coffee Break

11.20
Sulfuryl-transfer — Catalysis and Biology
Thomas S. Leyh, Albert-Einstein College of Medicine, Bronx, NY

12.00
How to Break a Carbon-Fluorine Bond — Assymmetry, Dynamics, Selectivity, and Inhibition in a Dehalogenation Reaction
Emil F. Pai, University of Toronto

12.40
Lunch

14.00
Translational Control: Probing Dimensionality Beyond Linear Sequence of mRNA
Zoya Ignatova, University of Hamburg

14.40
Metabolic Regulation from the Optimality Perspective
Bas Teusink, VU Universiteit Amsterdam

15.20
Tea Break

15.40
SABIO-RK: From Experiment to Database to Analysis
Wolfgang Müller, Heidelberg Institute for Theoretical Studies

16.20
Designing Enzyme Assays for the Accurate Measurement of Enzyme Kinetic Parameters
Santiago Schnell, University of Michigan Medical School, Ann Arbor, MI

17.00
STRENDA DB: The 'PDB' for Enzyme Function Data?
Johann Rohwer, University of Stellenbosch

19.30
Dinner